Experimental evaluation of a video streaming system for Wireless Multimedia Sensor Networks

Wireless Multimedia Sensor Networks (WMSNs) are recently emerging as an extension to traditional scalar wireless sensor networks, with the distinctive feature of supporting the acquisition and delivery of multimedia content such as audio, images and video. In this paper, a complete framework is proposed and developed for streaming video flows in WMSNs. Such framework is designed in a cross-layer fashion with three main building blocks: (i) a hybrid DPCM/DCT encoder; (ii) a congestion control mechanism and (iii) a selective priority automatic request mechanism at the MAC layer. The system has been implemented on the IntelMote2 platform operated by TinyOS and thoroughly evaluated through testbed experiments on multi-hop WMSNs. The source code of the whole system is publicly available to enable reproducible research. © 2011 IEEE

LAURA: LocAlization and Ubiquitous monitoRing of pAtients for health care support

This works illustrates the LAURA system, which performs localization, tracking and monitoring of patients hosted at nursing institutes by exploiting a wireless sensor network based on the IEEE 801.15.4 (Zigbee) standard. We focus on the indoor personal localization module, which leverages a method based on received signal strength measurements, together with a particle filter to perform tracking of moving patients. We discuss the implementation and dimensioning of the localization and tracking system using commercial hardware, and we test the LAURA system in real environment, both with static and moving patients, achieving an average localization error lower than 2 m in 80% of the cases. The data sets containing the real measurements of received signal strengths collected during the experiments are made publicly available to enable reproducible research

Le scelte degli amministratori nelle società eterodirette

Si prende in esame una serie di interessi (giuridicamente rilevanti) che gli operatori del diritto devono tenere in considerazione nel momento in cui si accingono a valutare il comportamento degli amministratori di una società controllata. In particolare, in relazione alle loro scelte gestorie tra tutela della società capogruppo e tutela della società eterodiretta della quale loro stessi sono amministratori. In seguito si cerca di illustrare il delicato rapporto tra le norme ex art. 2497 ter cc e 2391 cc a seguito della riforma del diritto societario, al fine di individuare se in Dottrina via sia una posizione comune ed univoca circa il comportamento che gli amministratori delle società eterodirette devono tenere nel momento in cui effettuano una scelta gestoria che sia influenzata da un interesse che “immediatamente” non si identifichi con l'interesse della società medesima. Si analizza la teoria che sembra essere prediletta dalla Giurisprudenza, la cd. teoria dei vantaggi compensativi, dando opinione sulla sua importanza a fine di risolvere il problema di coordinamento normativo.We analize the most important and rilevant interests that law operators must consider during their analisys about managers' way of taking decisions. This analisys put its attention on the relationship between companies under the control of other companies and in particular on the influence that the control may have on the result of manages' decisions. The aim of this work is to offer a clear view on the most important theory that today is the base of Courts' decisions. It criticizes this theory because it is useless to solve problems and on the other way, creates other problems due to its difficult interpretation.Discipline manageriali, finanziarie e giuridiche per la gestione integrata d'aziend

The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos

Mitochondrial membrane Protein Associated Neurodegeneration (MPAN) is a rare genetic disorder due to mutations in C19orf12 gene. In most cases, the disorder is transmitted as an autosomal recessive trait and the main clinical features are progressive spastic para/tetraparesis, dystonia, motor axonal neuropathy, parkinsonisms, psychiatric symptoms, and optic atrophy. Besides iron accumulation in the globus pallidus and substantia nigra, the neuropathology shows features also observed in Parkinson’s Disease brains, such as α-synuclein-positive Lewy bodies and hyperphosphorylated tau. Mutations in the gene have been found in other neurodegenerative disorders, including PD, hereditary spastic paraplegia, pallido-pyramidal syndrome, and amyotrophic lateral sclerosis. The biological function of C19orf12 gene is poorly defined. In humans, it codes for two protein isoforms: the longer one is present in mitochondria, endoplasmic reticulum, and contact regions between mitochondria and ER. Mutations in the gene appear to be linked to defects in mitochondrial activity, lipid metabolism and autophagy/mitophagy. To increase the available tools for the investigation of MPAN pathogenesis, we generated a new animal model in zebrafish embryos. The zebrafish genome contains four co-orthologs of human C19orf12. One of them, located on chromosome 18, is expressed at higher levels at early stages of development. We downregulated its expression by microinjecting embryos with a specific ATG-blocking morpholino, and we analyzed embryonal development. Most embryos showed morphological defects such as unsettled brain morphology, with smaller head and eyes, reduced yolk extension, tilted and thinner tail. The severity of the defects progressively increased and all injected embryos died within 7 days post fertilization. Appropriate controls confirmed the specificity of the observed phenotype. Changes in the expression and distribution of neural markers documented a defective neuronal development, particularly evident in the eyes, the optic tectum, the midbrain-hindbrain boundary; Rohon Beard and dorsal root ganglia neurons were also affected. Phalloidin staining evidenced a significant perturbation of musculature formation that was associated with defective locomotor behavior. These data are consistent with the clinical features of MPAN and support the validity of the model to investigate the pathogenesis of the disease and evaluate molecules with potential therapeutic effect

Development of BCR-ABL1 Transgenic Zebrafish Model Reproducing Chronic Myeloid Leukemia (CML) Like-Disease and Providing a New Insight into CML Mechanisms

Zebrafish has proven to be a versatile and reliable experimental in vivo tool to study human hematopoiesis and model hematological malignancies. Transgenic technologies enable the generation of specific leukemia types by the expression of human oncogenes under specific promoters. Using this technology, a variety of myeloid and lymphoid malignancies zebrafish models have been described. Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasia characterized by the BCR-ABL1 fusion gene, derived from the t (9;22) translocation causing the Philadelphia Chromosome (Ph). The BCR-ABL1 protein is a constitutively activated tyrosine kinas inducing the leukemogenesis and resulting in an accumulation of immature leukemic cells into bone marrow and peripheral blood. To model Ph+ CML, a transgenic zebrafish line expressing the human BCR-ABL1 was generated by the Gal4/UAS system, and then crossed with the hsp70-Gal4 transgenic line. The new line named (BCR-ABL1pUAS:CFP/hsp70-Gal4), presented altered expression of hematopoietic markers during embryonic development compared to controls and transgenic larvae showed proliferating hematopoietic cells in the caudal hematopoietic tissue (CHT). The present transgenic zebrafish would be a robust CML model and a high-throughput drug screening tool

Wages in the Business Cycle - an empirical and methodological analysis.

We propose an optimization-based framework to minimize the energy consumption in a sensor network when using an indoor localization system based on the combination of received signal strength (RSS) and pedestrian dead reckoning (PDR). The objective is to find the RSS localization frequency and the number of RSS measurements used at each localization round that jointly minimize the total consumed energy, while ensuring at the same time a desired accuracy in the localization result. The optimization approach leverages practical models to predict the localization error and the overall energy consumption for combined RSS-PDR localization systems. The performance of the proposed strategy is assessed through simulation, showing energy savings with respect to other approaches while guaranteeing a target accuracy